District 12 headquarters are located at the Texas A&M AgriLife Research & Extension Center in Weslaco.
| District 12 County Extension Office Phone Numbers |
|
| Atascosa County | (830) 769-3066 |
| Brooks County | (361) 325-4402 |
| Cameron County | (956) 361-8236 |
| Dimmitt County | (830) 876-4216 |
| Duval County | (361) 256-4591 |
| Frio County | (830) 334-0099 |
| Hidalgo County | (956) 383-1026 |
| Jim Hogg County | (361) 527-3169 |
| Jim Wells County | (361) 668-5705 |
| Kenedy County | (361) 595-8566 |
| Kleberg County | (361) 595-8566 |
| La Salle County | (830) 879-4448 |
| Live Oak County | (361) 449-1703 |
| Maverick County | (830) 773-5064 |
| McMullen County | (316) 274-3323 |
| Starr County | (956) 487-2306 |
| Webb County | (956) 721-2626 |
| Willacy County | (956) 689-2412 |
| Zapata County | (956) 765-9967 |
| Zavala County | (830) 374-2883 |